TABLE OF CONTENTS
1 INTRODUCTION 15
1.1 OBJECTIVES OF THE STUDY 15
1.2 MARKET DEFINITION 15
1.3 OVERVIEW OF MIDDLE EAST & AFRICA EXOCRINE PANCREATIC INSUFFICIENCY (EPI) THERAPEUTICS AND DIAGNOSTICS MARKET 15
1.4 LIMITATIONS 17
1.5 MARKETS COVERED 17
2 MARKET SEGMENTATION 20
2.1 MARKETS COVERED 20
2.2 GEOGRAPHICAL SCOPE 21
2.3 YEARS CONSIDERED FOR THE STUDY 22
2.4 CURRENCY AND PRICING 22
2.5 DBMR TRIPOD DATA VALIDATION MODEL 23
2.6 MULTIVARIATE MODELLING 26
2.7 PRODUCT TYPE LIFELINE CURVE 26
2.8 PRIMARY INTERVIEWS WITH KEY OPINION LEADERS 27
2.9 DBMR MARKET POSITION GRID 28
2.10 MARKET TESTING TYPE COVERAGE GRID 29
2.11 VENDOR SHARE ANALYSIS 30
2.12 SECONDARY SOURCES 31
2.13 ASSUMPTIONS 31
3 EXECUTIVE SUMMARY 32
4 PREMIUM INSIGHTS 34
4.1 PESTEL ANALYSIS 35
4.2 PORTER ANALYSIS 36
5 INDUSTRY INSIGHTS 37
6 REGULATORY FRAMEWORK 39
7 MARKET OVERVIEW 41
7.1 DRIVERS 43
7.1.1 INCREASING PREVALENCE OF EXOCRINE PANCREATIC INSUFFICIENCY (EPI) DUE TO CHRONIC PANCREATITIS AND CYSTIC FIBROSIS 43
7.1.2 RISING TECHNOLOGICAL ADVANCEMENTS IN DIAGNOSIS AND TREATMENT OF EPI 43
7.1.3 STRATEGIC INITIATIVES BY THE KEY MARKET PLAYERS 44
7.1.4 SEDENTARY LIFESTYLES AND UNHEALTHY DIETS 44
7.2 RESTRAINTS 45
7.2.1 STRINGENT REGULATIONS TO HAMPER THE EXOCRINE PANCREATIC INSUFFICIENCY(EPI) THERAPEUTIC AND DIAGNOSTIC SECTOR 45
7.2.2 SIDE EFFECTS AND RELIGIOUS HURDLES ASSOCIATED WITH PANCREATIC ENZYME REPLACEMENT THERAPY (PERT) 45
7.3 OPPORTUNITIES 46
7.3.1 INCREASING PREVALENCE OF PANCREATIC DISORDERS AND ASSOCIATED CONDITION 46
7.3.2 RISING AWARENESS ABOUT THE BENEFITS OF EARLY DIAGNOSIS AND TREATMENT OF EPI 46
7.3.3 GROWING DEMAND FOR COMBINATION THERAPIES AND PERSONALIZED MEDICINE 47
7.4 CHALLENGES 48
7.4.1 HIGH COST ASSOCIATED WITH EPI DIAGNOSIS AND TREATMENT 48
7.4.2 LIMITED AVAILABILITY OF EPI THERAPEUTICS AND DIAGNOSTICS 48
8 MIDDLE EAST & AFRICA EXOCRINE PANCREATIC INSUFFICIENCY (EPI) THERAPEUTICS AND DIAGNOSTICS MARKET, BY TREATMENT 49
8.1 OVERVIEW 50
8.2 PANCREATIC ENZYME REPLACEMENT THERAPY (PERT) 53
8.2.1 BY ENZYME 53
8.2.1.1 LIPASE 54
8.2.1.2 PROTEASE 54
8.2.1.3 AMYLASE 54
8.2.2 BY ROUTE OF ADMINISTRATION 54
8.2.2.1 ORAL 55
8.2.2.1.1 CAPSULES 55
8.2.2.1.2 TABLETS 55
8.2.2.1.3 POWDER 55
8.2.2.2 INTRAVENOUS 55
8.3 NUTRITIONAL MANAGEMENT 56
8.3.1 VITAMIN D 57
8.3.2 VITAMIN E 57
8.3.3 VITAMIN A 57
8.3.4 VITAMIN K 57
8.3.5 OTHERS 57
9 MIDDLE EAST & AFRICA EXOCRINE PANCREATIC INSUFFICIENCY (EPI) THERAPEUTICS AND DIAGNOSTICS MARKET, BY DIAGNOSIS 58
9.1 OVERVIEW 59
9.2 PANCREATIC FUNCTION TEST 61
9.2.1 STOOL 62
9.2.1.1 FECAL ELASTASE TEST 63
9.2.1.2 FECAL FAT TEST 63
9.2.2 SECRETIN PANCREATIC FUNCTION TEST 63
9.2.3 BLOOD TESTS 63
9.2.4 C-MIXED TRIGLYCERIDES BREATH TEST 63
9.2.5 FASTING PLASMA GLUCOSE TEST 63
9.3 IMAGING TEST 63
9.3.1 CT SCANNING 65
9.3.2 MAGNETIC RESONANCE IMAGING TESTS (MRI) 65
9.3.3 ENDOSCOPIC RETROGRADE PANCREATOGRAPHY 65
9.3.4 ENDOSCOPIC ULTRA-SONOGRAPHY (EUS) 65
9.3.5 SECRETIN-STIMULATED MAGNETIC RESONANCE CHOLANGIOPANCREATOGRAPHY 65
10 MIDDLE EAST & AFRICA EXOCRINE PANCREATIC INSUFFICIENCY (EPI) THERAPEUTICS AND DIAGNOSTICS MARKET, BY DRUG TYPE 66
10.1 OVERVIEW 67
10.2 BRANDED 69
10.2.1 CREON 70
10.2.2 ZENPEP 71
10.2.3 PANCREAZE 71
10.2.4 NUTRIZYM 71
10.2.5 PANCREASE MT 71
10.2.6 PANCREX 71
10.2.7 COTAZYM 71
10.2.8 ULTERSA 71
10.2.9 VIOKACE 71
10.2.10 PERTZYE 71
10.2.11 OTHERS 72
10.3 GENERIC 72
11 MIDDLE EAST & AFRICA EXOCRINE PANCREATIC INSUFFICIENCY (EPI) THERAPEUTICS AND DIAGNOSTICS MARKET, BY END USER 73
11.1 OVERVIEW 74
11.2 HOSPITALS 76
11.2.1 PRIVATE 77
11.2.2 PUBLIC 77
11.3 SPECIALTY CLINICS 77
11.4 DIAGNOSTIC CENTER 78
11.5 HOMECARE 79
11.6 RESEARCH AND ACADEMIC INSTITUTES 80
11.7 OTHERS 81
12 MIDDLE EAST & AFRICA EXOCRINE PANCREATIC INSUFFICIENCY (EPI) THERAPEUTICS AND DIAGNOSTICS MARKET, BY DISTRIBUTION CHANNEL 82
12.1 OVERVIEW 83
12.2 DIRECT TENDER 85
12.3 RETAIL PHARMACY 86
12.4 THIRD PARTY DISTRIBUTORS 87
12.5 OTHERS 88
13 MIDDLE EAST & AFRICA EXOCRINE PANCREATIC INSUFFICIENCY (EPI) THERAPEUTICS AND DIAGNOSTICS MARKET, BY REGION 89
13.1 MIDDLE EAST AND AFRICA 90
13.1.1 SOUTH AFRICA 94
13.1.2 SAUDI ARABIA 94
13.1.3 BAHRAIN 94
13.1.4 U.A.E. 94
13.1.5 KUWAIT 94
13.1.6 OMAN 94
13.1.7 QATAR 94
13.1.8 EGYPT 94
13.1.9 ISRAEL 94
13.1.10 REST OF MIDDLE EAST AND AFRICA 95
14 MIDDLE EAST & AFRICA EXOCRINE PANCREATIC INSUFFICIENCY (EPI) THERAPEUTICS AND DIAGNOSTICS MARKET: COMPANY LANDSCAPE 96
14.1 COMPANY SHARE ANALYSIS: MIDDLE EAST & AFRICA 96
15 SWOT ANALYSIS 97
16 COMPANY PROFILE 98
16.1 ABBVIE INC. 98
16.1.1 COMPANY SNAPSHOT 98
16.1.2 REVENUE ANALYSIS 98
16.1.3 COMPANY SHARE ANALYSIS 99
16.1.4 PRODUCT PORTFOLIO 99
16.1.5 RECENT DEVELOPMENT 99
16.2 ABBOTT 100
16.2.1 COMPANY SNAPSHOT 100
16.2.2 REVENUE ANALYSIS 100
16.2.3 COMPANY SHARE ANALYSIS 101
16.2.4 PRODUCT PORTFOLIO 101
16.2.5 RECENT DEVELOPMENT 101
16.3 NESTLE 102
16.3.1 COMPANY SNAPSHOT 102
16.3.2 REVENUE ANALYSIS 102
16.3.3 COMPANY SHARE ANALYSIS 103
16.3.4 PRODUCT PORTFOLIO 103
16.3.5 RECENT DEVELOPMENTS 103
16.4 LABORATORY CORPORATION OF AMERICA HOLDINGS (2022) 104
16.4.1 COMPANY SNAPSHOT 104
16.4.2 REVENUE ANALYSIS 104
16.4.3 COMPANY SHARE ANALYSIS 105
16.4.4 PRODUCT PORTFOLIO 105
16.4.5 RECENT DEVELOPMENT 105
16.5 JANSSEN MIDDLE EAST & AFRICA SERVICES, LLC 106
16.5.1 COMPANY SNAPSHOT 106
16.5.2 REVENUE ANALYSIS 106
16.5.3 COMPANY SHARE ANALYSIS 107
16.5.4 PRODUCT PORTFOLIO 107
16.5.5 RECENT DEVELOPMENT 107
16.6 ALCRESTA THERAPEUTICS, INC. 108
16.6.1 COMPANY SNAPSHOT 108
16.6.2 COMPANY SHARE ANALYSIS 108
16.6.3 PRODUCT PORTFOLIO 109
16.6.4 RECENT DEVELOPMENT 109
16.7 BIOSERV DIAGNOSTICS GMBH 110
16.7.1 COMPANY SNAPSHOT 110
16.7.2 PRODUCT PORTFOLIO 110
16.7.3 RECENT DEVELOPMENT 110
16.8 CILIAN AG 111
16.8.1 COMPANY SNAPSHOT 111
16.8.2 PRODUCT PORTFOLIO 111
16.8.3 RECENT DEVELOPMENT 111
16.9 CHIRHOCLIN 112
16.9.1 COMPANY SNAPSHOT 112
16.9.2 COMPANY SHARE ANALYSIS 112
16.9.3 PRODUCT PORTFOLIO 113
16.9.4 RECENT DEVELOPMENT 113
16.10 DIGESTIVE CARE, INC. 114
16.10.1 COMPANY SNAPSHOT 114
16.10.2 PRODUCT PORTFOLIO 114
16.10.3 RECENT DEVELOPMENT 114
16.11 EAGLEBIO 115
16.11.1 COMPANY SNAPSHOT 115
16.11.2 PRODUCT PORTFOLIO 115
16.11.3 RECENT DEVELOPMENT 115
16.12 METAGENICS LLC 116
16.12.1 COMPANY SNAPSHOT 116
16.12.2 PRODUCT PORTFOLIO 116
16.12.3 RECENT DEVELOPMENT 116
16.13 NORDMARK 117
16.13.1 COMPANY SNAPSHOT 117
16.13.2 COMPANY SHARE ANALYSIS 117
16.13.3 PRODUCT PORTFOLIO 118
16.13.4 RECENT DEVELOPMENT 118
16.14 ORGANON GROUP OF COMPANIES. 119
16.14.1 COMPANY SNAPSHOT 119
16.14.2 REVENUE ANALYSIS 119
16.14.3 PRODUCT PORTFOLIO 120
16.14.4 RECENT DEVELOPMENT 120
16.15 SCHEBO BIOTECH AG 121
16.15.1 COMPANY SNAPSHOT 121
16.15.2 PRODUCT PORTFOLIO 121
16.15.3 RECENT DEVELOPMENT 121
16.16 VIVUS LLC 122
16.16.1 COMPANY SNAPSHOT 122
16.16.2 COMPANY SHARE ANALYSIS 122
16.16.3 PRODUCT PORTFOLIO 123
16.16.4 RECENT DEVELOPMENT 123
17 QUESTIONNAIRE 124
18 RELATED REPORTS 127

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